Development of Bis-GMA-free biopolymer to avoid estrogenicity

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Nuclear magnetic resonance spectra of Bis-GMA and Iso-bis-GMA.

2, 2-Bis [4- (2-hydroxy-3-methacryloyloxypropoxy) phenyl] propane (bis-GMA) is widely used in dentistry as a monomer of composite resin system and their bonding agents. Since bis-GMA is not purified, its isomers and some chemicals such as residual initiator remain in the commercial product. Bis-GMA and iso-bis-GMA were separated from bis-GMA monomer by HPLC. NMR spectra of both monomers were re...

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سنتز مشتقات اورتانی bis-gma

اغلب کامپوزیت ها مخلوط فیزیکی مواد هستند که جسم توقویت شده ای را نتیجه می دهند. هدف برتر این پروژه ساخت مواد دندانی از نوع کامپوزیت می باشد. کامپوزیتهای دندانی را غالبا با عناوین رزین های پرشده رزین کامپوزیت می نامند. این مواد در اواسط دهه 1960 شناخته شدند اصطلاح کامپوزیت دندانی به شکل مرسوم بیانگر مخلوطی از شیشه های سیلیکات با مونومرهای آکریلی است که پلیمریزاسیون آنها هنگام اختلاط با شیشه آغاز...

15 صفحه اول

Preparation of a Bis-GMA-Free Dental Resin System with Synthesized Fluorinated Dimethacrylate Monomers

With the aim of reducing human exposure to Bisphenol A (BPA) derivatives in dentistry, a fluorinated dimethacrylate monomer was synthesized to replace 2,2-bis[4-(2-hydroxy-3-methacryloy-loxypropyl)-phenyl]propane (Bis-GMA) as the base monomer of dental resin. After mixing with reactive diluent triethyleneglycol dimethacrylate (TEGDMA), fluorinated dimethacrylate (FDMA)/TEGDMA was prepared and c...

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Apoptosis and survivability of human dental pulp cells under exposure to Bis-GMA

OBJECTIVE In the present study, we examined whether 2, 2-bis [4-(2-hydroxy-3-methacryloxypropoxy) phenyl] propane (Bis-GMA) has effects on LSC2 cells, human dental pulp cell line. MATERIAL AND METHODS The viability, cell cycle, and morphology of LSC2 cells were analyzed after exposure to several different concentrations of Bis-GMA. The recovery of viability of Bis-GMA exposed cells was also a...

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Synthesis of fluorinated Bis-GMA and its use with other fluorinated monomers to formulate hydrophobic composites.

Fluorinated Bis-GMA was synthesized and used with other commercially available fluorinated monomers and diluents to prepare hydrophobic composites. The composites were formulated as one-paste systems and were polymerized using blue light. Mechanical properties and water-related qualities were determined. Fluorination generally improved the hydrophobicity of the composites, but there was no clea...

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ژورنال

عنوان ژورنال: Dental Materials

سال: 2020

ISSN: 0109-5641

DOI: 10.1016/j.dental.2019.11.016